11 results
Algorithm for the differentiation between simple and complex febrile seizures. Guidelines for evaluation of each. #Diagnosis
Algorithm for the ... between simple and complex ... febrile seizures ... Diagnosis #Management #EM ... FebrileSeizure #Fever
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
produced from pathogens ... cell co-receptor complex ... Opsonization: Abs coat pathogens ... Neutralization: Abs bind to pathogen ... Humoral #Immunity #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... immunofluorescence Immune Complex ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
uncharacterized fevers ... (particularly complex ... febrile seizure ... Diagnosis #Peds #EM ... Classification #Fever
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
ID Approach to Fever ... Rash - Diagnostic Algorithm ... Secondary syphilis, EM ... #Rash #Febrile ... #Diagnosis #Algorithm
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... response to bacterial pathogens ... tissue -> Fatigue, fever ... #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, seasonal hay fever ... antigen, leading to complement ... Antigen-antibody complexes ... Complement activation ... Classification #Pathophysiology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Red Flags: • Fever ... medication Febrile ... Work Up: • Complete ... Differential #Diagnosis #Algorithm
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
response to a pathogen ... hypothalamus → fever ... • Chills in febrile ... PATHOPHYSIOLOGY: ... Rigors #Bacteremia #Pathophysiology
Suspected catheter-related bloodstream infection - Management Algorithm
 • Temperature 37.8 C   • Rigors
infection - Management Algorithm ... • Persistent fever ... • Persistent fever ... • Resistant pathogens ... options and is: • Afebrile