9 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... DDX - Other causes ... #immunology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
: • Most common ... Orange or Hep C Clinical ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Syndrome (CAS): ... Viral Infection Clinical ... symptoms - most common ... younger pts) Differential ... #anemia #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... Agranulocytosis • Hypogammaglobulinemia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... lymphoma (Richter ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... gastric tumors • Hematology ... anemia • Other ... Comment on type ... #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... Workup: • Full ... number of sites of disease ... #hematology #oncology ... #management
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Diagnosis Algorithm ... Better call hematology ... , think about common ... #Diagnosis #Algorithm ... #workup #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Most common cytopenia ... Marrow Failure • Chronic ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology