9 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... and extrinsic pathways ... in the common pathway ... to the common pathway ... amyloidosis #Abnormal
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... deficiencies: Contact pathway ... to the common pathways ... Jcortesizaguirr #Abnormal ... Causes #diagnosis #differential
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/ABNORMAL PTT ... the intrinsic pathway ... the extrinsic pathway ... in the common pathway ... and extrinsic pathways
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
fatality is rare Normal ... : The complement ... pathway is a non-specific ... alternative, or lectin pathway ... #pathophysiology
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
demyelination alters normal ... neurotransmitter pathways ... methionine (SAM) pathway ... Secondary #Causes #Differential ... #Diagnosis #Pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Idiopathic • Normal ... Complement: IgA ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... determine choice of pathway ... for users of the pathway ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... the classical pathway ... (see Complement ... proliferate and differentiate ... Humoral #Immunity #pathophysiology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... unknown • Final pathway ... sx overlap with normal ... during Delivery • Stable