10 results
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Adrenal Insufficiency ... Weakness, fatigue, nausea ... , hypotension, hyponatremia ... ) stimulation test ... #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Adrenal Insufficiency ... Diagnosis Algorithm ... skin (due to high ACTH ... hypoglycemia, Hyponatremia ... #StimTest #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... this out - If unclear ... (often the case ... #ACTH #Stimulation ... #Test #Endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
• ACTH stimulation ... aldosterone - Low in cases ... • ACTH stimulation ... stimulation test ... diagnosis #testing #endocrinology
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Insufficiency - ... Algorithm Step ... #Insufficiency ... #ACTH #Stimulation ... #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
Adrenal Insufficiency ... Diagnosis Algorithm ... pregnancy) Test 2: ACTH ... Stimulation - ... #endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Insufficiency - ... ACTH-Dependent ... #Insufficiency ... #Causes #endocrinology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
, oral cavity) Caused ... is decreased), hypernatremia ... the abdomen for adrenal ... tumors • The adrenal ... signs #symptoms #endocrinology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... of Adrenal Insufficiency ... Tuberculosis: can cause ... stimulation test ... addisons #disease #endocrinology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Adrenal Insufficiency ... Most Common Cause ... secondary AI, hyponatremia ... Adrenal Insufficiency ... Diagnosis #Management #Endocrinology