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diagnosis oncology rheumatology workup agglutinin antibodies causes chronic cold common hemolytic hypogammaglobulinemia immunodeficiency immunology leukemia lupus lymphocytic management mds myelodysplasia
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
(ANA) ANA or Anti-NucIear ... context of other symptoms ... likely it will be clinically ... Lymphoproliferative Disorders ... #diagnosis #differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
pylori test (GI symptoms ... function test, ANA ... IgA, IgG, IgM (CVID ... changes), high MCV anemia ... Causes #Workup #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... alopecia Differential ... Clinical Features ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Secondary Cold ... Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... workup #oncology #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disorder with hypogammaglobulinemia ... infection risk secondary ... to 8 years Clinical ... autoimmune hemolytic anemia ... hypogammaglobulinemia #immunology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... DDX: Rule Out Secondary ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
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