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diagnosis oncology rheumatology management algorithm anemia antibodies chronic classification cll cold cryofibrinogenemia cvid enzymes erythematosus hemolytic hepatology hodgkins hypogammaglobulinemia immunodeficiency
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Viral Infection Clinical ... - most common presentation ... younger pts) Differential ... #anemia #hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
(ANA) ANA or Anti-NucIear ... context of other symptoms ... likely it will be clinically ... Lymphoproliferative Disorders ... #diagnosis #differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... to 8 years Clinical ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
symptoms/signs ... urgent referral to secondary ... presence of metabolic syndrome ... or referral to secondary ... Liver #Enzymes #Differential
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cooled from the normal ... Cryofibrinogenemia Symptoms ... cryoglobulinemia Associated Disorders ... Antiphospholipid syndrome ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Clinical Features ... Induced Lupus: • Symptoms ... Kidney disease common
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Most common cytopenia ... DDX: Rule Out Secondary ... Myeloproliferative Disease ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... workup #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Hodgkin Lymphoma - Clinical ... ingestion • B symptoms ... number of sites of disease ... classification #hematology
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