9 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... Signs and Symptoms ... patients • +ANA ... • Antithyroid antibodies ... #workup #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... pylori test (GI symptoms ... function test, ANA ... anti-phospholipid antibodies ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Secondary Cold ... Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... Lymphocytosis on CBC ... #oncology #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Clinical Features ... Induced Lupus: • Symptoms ... titers > 1:80 • CBC
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... - Clinical Presentation ... ingestion • B symptoms ... Workup: • Full ... classification #hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
symptoms/signs ... presence of metabolic syndrome ... body mass index; FBC ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... DDX: Rule Out Secondary ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... changes (POEMS syndrome ... gastric tumors • Hematology ... abnormal free light ... #diagnosis #hematology