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oncology algorithm management anemia causes cll leukemia lymphocytic rheumatology agglutinin bandemia biliary cholangitis cirrhosis classification cold common cryofibrinogenemia cvid elevatedmcv
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... decreased PLT count: CBC ... pylori test (GI symptoms ... function test, ANA ... #Workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
• Small Bowel Disorder ... Myelodysplastic Syndromes ... • Rule out B12 and ... Deficiency - Abnormal ... #Causes #Hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... Signs and Symptoms ... • Antithyroid antibodies ... PBC Diagnosis ... #workup #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Secondary Cold ... Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... hemolytic #anemia #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
: < 1% Clinically ... or "S" shaped nuclei ... • Autoimmune diseases ... #WBC #CBC #hematology ... #pathophysiology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... immunophenotype Clinical ... Vmphocytosis on routine CBC ... 3) Monoclonal antibodies ... Leukemia #oncology #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
symptoms/signs ... presence of metabolic syndrome ... body mass index; FBC ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Lymphocytosis on CBC ... #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Induced Lupus: • Symptoms ... titers > 1:80 • CBC ... with Lupus: • Chronic
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... to 8 years Clinical ... Autoimmunity • Chronic ... hypogammaglobulinemia #immunology #hematology
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