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management pediatrics febrile peds rheumatology antibiotics hlh lp lymphohistiocytosis risk stepbystep activation dermatology diagnossi differential ebm erythematous incomplete kd macrophage
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... Antibiotics #Risk #Stratification ... #Fever
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... Criteria - Fever ... #rheumatology # ... pediatrics #diagnossi ... #management #treatment
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... syndrome (SSS) in infants ... includes Kawasaki ... disease, scarlet ... #Diagnosis #Dermatology
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... EBM #Management #Pediatrics ... Antibiotics #Risk #Stratification ... #Fever
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... frequently affects infants ... age, however the disease ... following: • Fever ... #hematology
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
Disease 1. ... Infants ≤6 months ... echo is positive, treatment ... #Diagnosis #Peds ... #Pediatrics #Kawasaki
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
A subset of hemophagocytic ... erythematosus • Kawasaki ... is the main clinical ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... • Autoimmune diseases
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