7 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
, Behcet disease ... Complex: Systemic lupus ... erythematosus, Rheumatoid arthritis ... Investigations • Labs ... differential #diagnosis #nephrology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... azathioprine #Behcet ... management #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... ANCA-associated vasculitis ... Cytopenias • Cardiac valve ... : • Symptoms limited ... flares • CRP normal
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Behçet Syndrome ... - Recurrent oral ... such as systemic lupus ... Presentation - Systemic Symptoms ... retinopathy Lab
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... cognitive impairment, neurologic ... • Behcet syndrome
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... with systemic, neurologic ... or sed rate): Value ... 50 in GCA, but normal ... values increase
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Diagnosis: • Labs ... and Ohio River valleys ... by culture or serology ... level • A low or normal ... Meningitis, septic arthritis