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oncology leukemia lymphocytic workup abg acidbase agglutinin base bloodgas classification cold cvid erythematosus gap gas globulin hemeonc hemolytic hodgkins hypogammaglobulinemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... symptoms - most common ... younger pts) Differential ... Symptoms: High fevers ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... Lymphadenopathy • Fevers ... Physical Exam/Signs ... • Neutropenia, anemia ... workup #oncology #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... autoimmune hemolytic anemia ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... ) B symptoms → fevers ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Most common cytopenia ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... vitamin B12 or folic acid ... #diagnosis #hematology
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Acid Base Disorders ... L L-lactate (common ... D-lactate (short bowel syndrome ... Anxiety, pain, fever ... restrictive lung disease
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... common • Antihistone ... with Lupus: • Chronic ... #Rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Diagnosis Algorithm ... Better call hematology ... /high - Chronic ... #Diagnosis #Algorithm ... #workup #hematology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
- Anasarca - Fever ... , including acid ... severe fever with ... phosphatase - Normal ... #management #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... Nodosa: • PAN most commonly ... fluid (CSF) is abnormal ... Eosinophilia, asthma, chronic ... #Diagnosis #Rheumatology
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