11 results
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... inflammatory disorders ... Myelodysplastic syndrome ... #hematology #secondary
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Physical Exam/Signs ... lymphoproliferative disorders ... • Neutropenia, anemia ... workup #oncology #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Secondary Cold ... Agglutinin Syndrome ... younger pts) Differential ... Symptoms: High fevers ... #hematology #diagnosis
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
into a 4-pass system ... Eosinophilic GI Disorders ... Causes: • Mast cell ... activation syndrome ... #Diagnosis #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Diagnosis Algorithm ... Myelodisplastic syndrome ... #systemic #generalized ... #dermatology #Differential ... #Diagnosis #Algorithm
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... #diagnosis #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... blood count with differential ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... to: Arthritis, Fever ... with Lupus: • Chronic