Peds diagnosis algorithm syndrome signs management differential fever disorders hematology chronic pruritus alopecia disease systemic secondary hypogammaglobulinemia common hair

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Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
• Scarring Alopecia:

Allopecia - Differential ... , Loose anagen syndrome ... Examination: • Signs ... weight loss • Chronic ... Diagnosis #dermatology

Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell

Immunodeficiency disorder ... infection risk secondary ... hemolytic anemia) • Systemic ... #immunology #hematology ... #diagnosis #management

Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
• Lymphocytes accumulate in large numbers

Epidemiology: • Most common ... Lymphadenopathy • Fevers ... Physical Exam/Signs ... cells can indicate disease ... lymphoproliferative disorders

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

weight loss, and fever ... and permanent alopecia ... Differential ... common • Antihistone ... with Lupus: • Chronic

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