16 results
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Overview: • Most common ... immunophenotype Clinical ... Complications: 1) Infection ... chemotherapy for low-risk disease ... hemeonc #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Lymphoma - Clinical ... ingestion • B symptoms ... (NSHL) - (most common ... #oncology #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... Orange or Hep C Clinical ... with no early symptoms ... weeks without infection ... • Neutropenia, anemia
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Granulomatous lymphocytic ... hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... , autoimmune disorder ... Clinical Presentation ... - most common presentation ... pts) Differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... • Goodpasture syndrome ... • Giant cell arteritis ... disease • Non-Hodgkin
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... Arthralgia and Arthritis ... Malignancy Risk: • Non-Hodgkins ... #Rheumatology # ... Diagnosis #Management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... rheumatologic diseases ... fibromyalgia) • Infections ... Induced Lupus: • Symptoms ... common • Antihistone
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
effects of SCC or Hodgkin ... , rheumatoid arthritis ... life-threatening Differential ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Nodosa: • PAN most commonly ... • Progressive symptoms ... elevated protein, lymphocytic ... tract, and often causes ... #Diagnosis #Rheumatology