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diagnosis classification hematology vasculitis cvid dermatologic dermatology encephalopathy erythematosus giantcell gpa granulomatosis hypogammaglobulinemia immunodeficiency immunology lupus lymphoma neurology oncology polyangiitis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Lymphoma - Clinical ... ingestion • B symptoms ... (NSHL) - (most common ... #oncology #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Granulomatous lymphocytic ... hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... • Goodpasture syndrome ... • Giant cell arteritis ... disease • Non-Hodgkin
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
arteritis (GCA) ... Diagnosis = clinical ... vasculitis vs infection ... systemic complaints- anemia ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
develop in pts with GCA ... Nodosa: • PAN most commonly ... elevated protein, lymphocytic ... tract, and often causes ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... and branches • GCA ... to exclude are infections ... testes -> pain, infarct ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... rheumatologic diseases ... fibromyalgia) • Infections ... Induced Lupus: • Symptoms ... common • Antihistone
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
/Sepsis/Shock, Autoimmune ... disease, Cancer ... being the most common ... Neurological symptoms ... #diagnosis #management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... ethnicities Symptoms ... Polyarteritis Nodosa, GCA ... Polychondritis #rheumatology ... #diagnosis #management
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