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oncology anemia chronic cll disease leukemia lymphocytic symptoms workup agglutinin algorithm aplastic arteritis behcet classification cvid gca giantcell hemeonc hemophagocytic
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Agglutination - Cold ... Schistocytes, thrombocytopenia ... cardiac valve, vasculitis ... inclusions - If infection ... #workup #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Clinical Presentation ... symptoms - most common ... Diagnosis: • hemolytic ... #anemia #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... specifically immune thrombocytopenia ... and autoimmune hemolytic ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Overview: • Most common ... immunophenotype Clinical ... Complications: 1) Infection ... Leukemia #oncology #hematology ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... : HLH signs and ... symptoms can mimic common ... #management #treatment ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
of age • Most common ... Behcet disease) Differential ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... diagnosis = vasculitis ... vs infection vs ... them, but urgent rheumatology ... #Management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... Orange or Hep C Clinical ... weeks without infection ... Physical Exam/Signs ... workup #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... /fevers • Thrombocytopenia ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... nodosum • Immune hemolytic ... classification #hematology ... #oncology #management
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