4 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Positive Coombs testing ... younger pts) Differential ... chills, flank pain ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... cardiac valve, vasculitis ... #Diagnosis #Algorithm ... #workup #hematology ... #testing
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
[SLE], AOSD) • ... Infection (eg, ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
with excessive macrophage ... age, however the disease ... testing for HLH-associated ... #management #treatment ... #hematology