Petechial Rash Algorithm workup disease rheumatology hematology differential causes classification vasculitis bruising hodgkins mds bleeding gpa syndromes erythematosus types

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Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and

GPA causes disease ... • Goodpasture syndrome ... disease • Non-Hodgkin ... #dermatology #rash ... #diagnosis #rheumatology

Cryoglobulinemia Summary

Cryoglobulins:
• Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below

• Autoimmune diseases ... - GPA, EGPA, microscopic ... systemic lupus erythematosus ... #classification ... #rheumatology #

Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
•

> PR3 60% • GPA ... tract, and often causes ... mucositis - Rash ... #rheumatology # ... classification

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

Classification: ... permanent alopecia Differential ... • Type-I Interferonopathies ... cyclophosphamide) • Hodgkin ... #Diagnosis #Rheumatology

Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly

Easy or unusual bruising ... by bleeding (petechiae ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology

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