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oncology chronic differential lymphocytic agglutinin cold erythematosus gap globulin hemeonc hemophagocytic hodgkins hypogammaglobulinemia immunodeficiency immunology lupus lymphohistiocytosis lymphoma pancytopenia protein
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Cancer: • Leukemia ... Inflammatory and Autoimmune ... erythematosus • HLH ... #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... Overview: • Most common ... chemotherapy for low-risk disease ... #oncology #hematology ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... Physical Exam/Signs ... cells can indicate disease ... • Neutropenia, anemia ... #oncology #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... : Pneumonia • Autoimmune ... hemolytic anemia ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... symptoms - most common ... Diagnosis: • hemolytic ... #hemolytic #anemia ... #hematology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... : HLH signs and ... symptoms can mimic common ... #management #treatment ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... (NSHL) - (most common ... number of sites of disease ... #hematology #oncology ... #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... rheumatologic diseases ... common • Antihistone ... Hodgkin lymphoma and leukemia ... #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gastric tumors • Hematology ... anemia • Other ... Comment on type ... #differential #diagnosis ... #hematology
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