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oncology algorithm generalized pruritus systemic agglutinin classification cold common extravascular hemeonc hemolysis hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular lymphocytic lymphoma mds
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... • Intrinsic RBC ... #differential # ... diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... myeloid leukemia ... #Diagnosis #Causes ... #hematology #secondary
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... chemotherapy for low-risk disease ... AIHA, PRCA) • Treatment ... #hematology #hemeonc ... #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... Diagnosis: • hemolytic ... pts) Differential ... #hemolytic #anemia ... #hematology #diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... Throbocythemia • Myelodisplastic ... Pruritus #primary #secondary ... #generalized #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... #Pruritus #secondary ... #generalized #dermatology ... #causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... Marrow Failure • Chronic ... #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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