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diagnosis differential atlas bloodcell causes chronic common cvid fatigue gap globulin hemolytic hypogammaglobulinemia immunodeficiency immunology management mcv microscopy morphology nomenclature
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
McLeod blood group phenotype ... , Liver disease, ... spherocytosis, Autoimmune ... Agglutinate: Cold autoimmune ... differential #diagnosis #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... - Extrinsic: Autoimmune ... Non-megaloblastic: Liver ... #MCV #Algorithm ... Differential #Diagnosis #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Renal Failure • Liver ... Neoplastic / Hematologic ... • Anemia • ... Epstein-Barr Virus • Hepatitis ... • HIV Autoimmune
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... disease (diverse genotypes ... elliptocytosis, autoimmune ... #workup #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... diseases and hepatitis ... : Pneumonia • Autoimmune ... hemolytic anemia ... hypogammaglobulinemia #immunology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
first step in evaluation ... Sarcoidosis) • Liver ... Cirrhosis, ETOH, autoimmune ... gastric tumors • Hematology ... differential #diagnosis #hematology
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