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diagnosis differential injury lfts management causes transaminitis abnormal aclf aflp alcoholic bleeding bruising cancer chemistry chronic cirrhosis druginduced enzymes failure
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Hepatopathy • Acute ... Viral Hepatitis ... (>1000): • DILI ... Differential #Diagnosis #hepatology
Focused evaluation algorithm for acute liver injury #Liver #Injury #Acute #Evaluation #Algorithm #Diagnosis #Hepatology
Focused evaluation ... algorithm for acute ... liver injury ... Acute #Evaluation ... #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... dechallenge • Acute ... • Autoimmune hepatitis ... #Diagnosis #Algorithm ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Alcohol-Associated Hepatitis ... Injury (DILI) ... Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Tests of synthetic function ... differential #diagnosis #algorithm ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... • Infectious: Hepatitis ... , Acute biliary ... Diagnosis #Causes #Acute ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... viral hepatitis ... Chronic viral hepatitis ... Unconjugated Bili ... #differential #Hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... 10x ULN), ↑Tbili/Dbili ... Diagnosis: Viral Hepatitis ... #Pregnancy #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
hepatic synthetic function ... • Cirrhosis/acute ... hepatitis • Infiltrative ... sarcoidosis) • Liver ... Diagnosis #causes #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... indicate the initial evaluation ... history alongside evaluation ... #Hepatology #Liver
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