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diagnosis rheumatology msk pain antimda5 antimda5dm approach bone dermatologic dermatomyositis disease effusions gap globulin gpa granulomatosis knee physicalexam polyangiitis protein
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
): • Septic joint ... Like in this case ... #rheumatology # ... approach #workup ... #differential #
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Osteomyelitis / Septic ... Arthritis: • ... • Differentiate ... #hematology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... - Differential ... Fever/Chills/Joint ... Knee Effusions - Septic ... #differential #
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
interphalangeal joints ... • Arthralgia/arthritis ... Phenotype 2 ... muscle weakness Phenotype ... #dermatology #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... surfaces of the joints ... reticularis Differential ... • Giant cell arteritis ... Polyangiitis #GPA #dermatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... (RA, Temporal arteritis ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
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