15 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
): • Septic joint ... Like in this case ... #rheumatology # ... approach #workup ... #differential #
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Osteomyelitis / Septic ... Arthritis: • ... • Differentiate ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... for secondary causes ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... smear, HIV/HCV testing ... or if a primary hematologic ... #Workup #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... disease (diverse genotypes ... Hemolytic #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential ... Fever/Chills/Joint ... Knee Effusions - Septic ... #differential #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... Morning stiffness lasting ... weeks) Can Be Caused ... Joint #pain #Differential ... Diagnosis #MSK #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
interphalangeal joints ... • Arthralgia/arthritis ... Phenotype 2 ... muscle weakness Phenotype ... #dermatology #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic ... of the affected joint ... • Sacroiliac joint ... #laboratory #workup
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... surfaces of the joints ... reticularis Differential ... • Giant cell arteritis ... Polyangiitis #GPA #dermatology