6 results
diagnosis hepatology algorithm obstetrics pregnancy biliary causes chemistry cholangitis cirrhosis comparison disease fatty icp injury interpretation liverenzymes management obgyn pathophysiology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Pruritus, Mild jaundice ... , no necrosis HELLP ... #obstetrics #hepatitis ... #comparison #differential ... #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... , HELLP Moderate ... • Alcoholic hepatitis ... • Others #LFTs
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... (DIC, ascites, jaundice ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Preeclampsia, HELLP
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... replaced by non-hepatic ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... • Pregnancy: HELLP ... #differential #
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
hyperpigmentation • Jaundice ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... malignancies, Hepatic ... cholangitis #diagnosis #workup
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