12 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... bile ducts Differential ... cholangitis #diagnosis #workup
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
or the anterior chest ... (in a V-sign), ... Inverse Gottron’s sign ... auricular papules Clinical ... severity of the disease
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential ... 109 mm Hg) with clinical ... Renal parenchymal disease ... #causes #Differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Presentation: - Disease ... - Causes progressive ... course of the disease ... conditions listed in differential
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
Pathogenesis and Clinical ... mellitus, thyroid disease ... a stroke that caused ... diagnosis #symptoms #signs ... stages #staging #msk
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... renal failure Clinical ... symptoms are not caused ... anterior/posterior MSK ... Diagnosis #Management #Signs
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Generalized fatigue - ALS ... test - Cogan sign ... - Peek sign ... Imaging - CT Chest
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... • Bilateral signs ... • Infectious causes ... management #neurology #differential
On the left a chest film of a 19 year old patient with Langerhans cell histiocytosis.
The
this pattern was caused ... the central dot sign ... many inhalational diseases ... #Clinical #Radiology ... #CXR #CTChest #
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... number of sites of disease ... scans and can also