65 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... severity of the disease ... • Mechanic's hands
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
The signs and symptoms ... the palms of the hands ... resembling rashes caused ... #Diagnosis #Clinical ... #Photo #Dermatology
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... painless, no systemic signs ... biopsy preferred Differential ... University Infectious Diseases ... #photo #hand
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... • Infiltrative diseases ... Veno-occlusive disease ... #Diagnosis #causes
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
rigors, diarrhea, nausea ... critical illness ... cxs identify GNR and ... BIDMC Infectious Diseases ... #clinical #photo
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
structural heart disease ... syncope (ruling out differential ... orthostatic vital sign ... should be guided by clinical ... the underlying disease
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Passive neck flexion causes ... cord movement and ... While the pathophysiology ... despite severe disease ... #Meningitis #Clinical
Dermatomyositis
A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
This is a case of ... 1) heliotrope rash ... , 2) shawl sign, ... Gottrons #Papules #Clinical ... #Photo
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Clinical Findings ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... geriatrics #diagnosis #signs
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings ... share the same pathophysiology ... • Other rare causes ... Cardiovascular disease ... Overproduction #diagnosis #signs