15 results
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
Summary of dosing ... recommendations in renal ... #Diabetic #Medications ... #Pharmacology # ... Renal #Impairment
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
Metformin Current ... Renal Dose Adjustments ... #Renal #Dosing ... #Dose #Pharmacology ... #Diabetes
Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or
Metformin Treatment ... Patients With Type 2 Diabetes ... 3A, 3B, or 4 Diabetes ... #CKD3 #CKD4 #Dosing ... #Pharmacology #
Algorithm for Metformin Prescribing and Dosing in CKD
Dose Initiation - Immediate release:
 • Initial 500 mg
Algorithm for Metformin ... Prescribing and Dosing ... #Prescribing #Dosing ... #CKD #pharmacology ... #algorithm #diabetes
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Metformin - First ... Treatment for Diabetes ... form and consider using ... Indications #Titration #Pharmacology ... #Diabetes #DM2
Metformin: Biguanide
Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
treatment of type 2 diabetes ... 2000 mg/day) and using ... attention to patients renal ... #Pharmacology # ... Mechanism #Diabetes
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
Metformin in Diabetic ... eGFR < 30: Stop metformin ... annually if on metformin ... #CKD #pharmacology ... #algorithm #management
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Summary Mechanisms ... EricsMedicalLectures/ #Metformin ... #Pharmacology # ... Summary #DM2 #diabetes
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... Summary Vasopressors ... Phenylephrine ... 2 mcg/kg/min): renal ... #Summary #management
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Inhibitors - Normal and Renal ... Dosing Increase ... patients have renal ... #Dosing #Pharmacology ... #Management #Diabetes