14 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Crises can be precipitated ... The underlying pathophysiology ... 2) Aplasia - Acute ... #Features #Signs ... #Symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... • Salt wasting crisis ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
muscles: “myasthenic crises ... life-threatening Differential ... Myasthenia Crises ... aspiration and acute ... diagnosis #management #neurology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
Edema (NCPE) - Differential ... of acute respiratory ... • Signs/Symptoms ... • Signs/Symptoms ... #differential #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
• Hypertensive crisis ... Etiology: • Pathophysiology ... Neurological symptoms ... : Acute onset 2 ... Reversible course Differential
13 Dangerous Causes of Headache:
 - subarachnoid hemorrhage: family history, PCKD, known berry aneurysm, sudden and
13 Dangerous Causes ... or at work) - acute ... thrombophilia, neurologic ... signs/symptoms ... Dangerous #Deadly #Differential
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
Coltivirus Symptoms ... influenzae Symptoms ... : • Acute meningeal ... signs (fever, nuchal ... #diagnosis #neurology
Avascular Necrosis: Pathogenesis and Clinical Findings
 • Physical Trauma (esp. to the scaphoid bone with damage
disease (sickle crisis ... ) • Multiple causes ... affected) - Acute ... AvascularNecrosis #pathophysiology ... #symptoms
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
: 1) Acute kidney ... anemia (MAHA) Pathophysiology ... , add other BP meds ... • Refractory cases ... #rheumatology #nephrology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... fasciculations Common Symptoms ... conditions listed in differential ... Lateral #Sclerosis #neurology