11 results
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... • Infection - ... skin flora (GPCs ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Infection - Infection ... skin flora (GPCs ... Transfusion #diagnosis #management ... #hematology #reactions
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... SLE) - Viral infections ... Kasabach-Merritt syndrome ... fever • Drug reactions ... #rheumatology #
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
of fibrin split products ... • Fibrin split products ... Malignancy • Infections ... cryoglobulins • Negative causes ... Antiphospholipid syndrome
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... Neutropenia - recurrent infections ... and petechiae Causes ... Idiopathic • Infections ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... • Cogan Syndrome ... disease, drug reactions ... to exclude are infections ... differential #diagnosis #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... Rule out other causes ... such as infectious ... #Rheumatology # ... diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
disease, drug reactions ... to exclude are infections ... tract, and often causes ... , recent viral infection ... Differential #Diagnosis #Rheumatology
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
responsible for most cases ... → Ulcerates to produce ... weight loss • Skin ... Albuminuria, nephrotic syndrome ... stages #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... superinfection, drug reactions ... cavitating pneumonia, skin ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management