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diagnosis causes algorithm oncology rheumatology systemic generalized pruritus agglutinin blurry classification cold cryofibrinogenemia cutaneous disease hemolytic hodgkins lymphoma management mds
Blurry Vision - Differential Diagnosis Framework Anatomical Approach to Eye Disease: 1. Lids/Lashes 2. Extraocular Muscles/Motility 3. Conjunctiva/Sclera 4. Cornea 5. Anterior
Blurry Vision - Differential ... : • Detachment ... • Sjögren’s syndrome ... retinopathy (sickle cell anemia ... hyperviscosity syndrome
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology ... #secondary
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... • Nephrotic syndrome ... NailDisorders #Systemic #Secondary ... #dermatology #Differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... - Hemolytic anemia ... #Diagnosis #hematology ... #nonpalpable #dermatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Involving the Skin - Differential ... Leukocytoclastic Vasculitis Secondary ... IgM deposits • Nodular ... Disease • Cogan syndrome ... Vasculitis #skin #dermatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
- Generalized Differential ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder Secondary ... Cold Agglutinin Syndrome ... younger pts) Differential ... #hematology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Hypergammaglobulinemic macular ... (-) hemolytic anemia ... vascular beds-renal, retinal ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Secondary form associated ... pulmonary emboli, and ocular ... thrombi including retinal ... Antiphospholipid syndrome ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... • Aplastic Anemia ... blood count with differential ... #diagnosis #hematology
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