12 results
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
• Loose anagen syndrome ... decalvans - Secondary ... to Skin Disease ... areata • Secondary ... #dermatology #Differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #dermatology #Differential
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... • Nephrotic syndrome ... NailDisorders #Systemic #Secondary ... #dermatology #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... Hepatosplenomegaly and generalized ... with leukopenia, anemia ... Diagnosis #Management #Hematology ... #Rheumatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
renal failure/uremia ... Myelodisplastic syndrome ... #Pruritus #secondary ... #systemic #generalized ... #dermatology #Differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder Secondary ... Cold Agglutinin Syndrome ... • Symptoms of anemia ... #hematology #diagnosis
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
SAPHO syndrome ( ... Acute generalized ... Secondary syphilis ... Sweet syndrome ... Differential #Diagnosis #Dermatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... autoimmune hemolytic anemia ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... • Aplastic Anemia ... Myeloproliferative Disease ... #diagnosis #hematology