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differential rheumatology amiodarone antibiotic bacilliformis bartonella catatonia failure hematology hyperthermia immune induced inflammatory iris leukostasis lung lysis malignant neuroleptic oroya
Comparison - Serotonin Syndrome, Neuroleptic Malignant Syndrome, and Malignant Catatonia - BWH Medicine Chiefs @BrighamChiefs #Serotonin #Syndrome #Neuroleptic
Comparison - Serotonin ... Malignant #Catatonia #NMS ... #SS #comparison ... #diagnosis #management ... #treatment #table
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... jaundice ​• Neuro: AMS ... → Mular DIAGNOSIS ... TREATMENT: ​• Acute ... #diagnosis #management
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Drug-related (NMS ... , serotonin syndrome ... CNS, prostate, ocular ... • Secondary to Treatment ... SJS, DIHS, drug fever
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... - 80% have fever ... organ damage • Treatment ... #TLS #diagnosis ... #management #hematology
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
Presentation: Fever ... Albuminuria, nephrotic syndrome ... Headache, meningitis, ocular ... Syphilis #stages #diagnosis ... #management #Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... skin lesions, ocular ... Zoster flare, ocular ... #Inflammatory #Syndrome ... #Management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... respiratory distress syndrome ... Fever 4. ... macrophages Treatment ... #management #Toxicology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
- Anasarca - Fever ... without TAFRO (iMCD-NOS ... disease, severe fever ... Hypoalbuminemia Treatment ... #management #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Nonspecific symptoms: Fever ... chondritis • Ocular ... /EGPA • RA Diagnosis ... affected tissue Treatment ... #management
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