11 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... partial retinal red reflex ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Mutism Pathophysiology ... • Vestibulo-ocular ... myoclonic movements, tremors ... • Examine for signs ... caseyalbin #PhysicalExam
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
 - General - From asymptomatic to myxedema coma, “Like
- Symptoms and Signs ... Thinning of lateral 1/ ... Insomnia • Tremour ... ophthalmopathy ocular ... #Diagnosis #endocrinology
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
normal: - extra-ocular ... - pupillary reflex ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
endemic areas - 1- ... cases Clinical Signs ... years - May have signs ... numbness, decreased reflexes ... Pathophysiology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Perforation) Pathophysiology ... Epidemiology: • #1 ... often ordered in reflex ... • Flex-Sig: If ... 10 mg/kg IV x 1
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Hypertension Stage 1: ... diffuse light reflex ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
Symptoms and Signs ... Hypertension: 1/ ... common symptoms and signs ... hypotension (may reflect ... phenoxybenzamine blocks alpha-1
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... ALS involves: (1) ... Increased Jaw Jerk reflex ... likelihood of this 1. ... #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... ) Differential Diagnosis ... interferon alfa, or tumor ... inhibitors • Uveitis- Ophthalmology ... #management #signs