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rheumatology causes erythematosus lupus systemic testing ana antinuclear laboratory nuclear patterns workup acidosis arthritis autoantibodies clinicopathology criteria cytoplasmic dermatology disease
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... pericarditis • Hematologic ... #EULARACR #Classification ... #Criteria #SLE ... Erythematosus #diagnosis
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Smith, Sm/RNP, Scl ... #Antinuclear #Antibody ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... involvement 3% SLE-Related ... ) 30-45% Differential ... Lupusreference #SLE ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... test, ANA (e.g., SLE ... changes), high MCV anemia ... not required in all
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... rubella titer, ACE ... (to support a diagnosis ... laboratory #workup #diagnosis
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
concept is that all ... antineutrophil cytoplasmic antibody ... #Diagnosis #Rheumatology ... #Differential # ... Medium #Large #Classification
Types of Melanoma Superficial Spreading • Most common form • Often develops in previously benign mole •
• 10-15% of all ... eye you cannot see ... Melanoma #Types #differential ... #diagnosis #classification ... #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... erythematosus (ACLE ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... lymphopenia, low PLT • Anemia
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... Homogeneous pattern: • SLE ... pattern: • SjS, SLE ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... #classification ... #hematology #oncology
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