4 results
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
blood culture negative ... whipplei, Fungi (Aspergillus ... #Causes #differential ... causes #culture #negative ... #BCNIE #cardiology
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... cultures remain negative ... antimicrobials, clinical ... whipplei, Fungi (Aspergillus ... Endocarditis #diagnosis #differential
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Coccidioides - Negative ... cut-offs defined in clinical ... Cryptococcus - Negative ... BAL GM does not differentiate ... Galactomannan #diagnosis #comparison
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
use: Candida, Aspergillus ... Almost always negative ... cut-offs defined in clinical ... >90% (In most clinical ... in BAL does not differentiate