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anemia differential aflp causes cold obstetrics pregnancy table thrombocytopenia ttphus workup agglutinin autoimmune classification disease enlarged extravascular hemolysis hepatitis hepatology
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Lymphoproliferative disorder ... , Autoimmune disorder ... Mycoplasma, HIV, EBV ... #Anemia #hematology ... #diagnosis #comparison
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... coagulation (DIC) - HELLP ... lymphoproliferative disorders ... #differential #diagnosis ... #hematology #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... thrombocytopenia - DIC, TTP, HELLP ... Consider RBC membrane disorder ... #hematology #testing
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Algorithm Infectious ... Bacterial • Viral (EBV ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... workup, including BM ... blood loss, Acute hemolysis ... #Algorithm #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Pregnancy - TTP/HUS, HELLP ... (Hemolysis, Elevated ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
coagulation defects. 1) HELLP ... (Hemolysis, Elevated ... Pregnancy #TTPHUS #HELLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Diagnosis: • hemolytic ... - Mycoplasma, EBV ... #anemia #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... ) ablative disorders ... #Diagnosis #Workup ... #Hematology #Microcytic
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... HBV, HCV, HEV, EBV ... • Pregnancy: HELLP ... #algorithm #hepatology
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