52 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
) • Systemic lupus ... Vasculitis: • ... + 90% • Anti-GBM ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
Vasculitis A group ... , small-vessel vasculitis ... rarely PR3 Anti-GBM ... MPO #PR3 #Diagnosis ... #Rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Vasculitis: P-ANCA ... Autoantibodies #Rheumatology ... #diagnosis #associations
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... #rheumatology #
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... Nodosa (PAN), ANCA ... associated vasculitis ... (RA), Systemic lupus ... #rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA) - ANCA ... Vasculitis Management ... Algorithm - ACR ... #Vasculitis #Management ... #rheumatology
Diagnosis and management of Polyarteritis Nodosa (PAN)

Chapel Hill 2012 definition: 
Necrotizing vasculitis ofmedium or small arteries
Diagnosis and management ... Necrotizing vasculitis ... associated with ANCA ... PolyarteritisNodosa #Rheumatology ... #Diagnosis #Management
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... Vasculitis There ... StanfordChiefs #ANCA ... #diagnosis #algorithm ... #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Active
Polyangiitis (EGPA) - ANCA ... Vasculitis Management ... Algorithm - ACR ... #Vasculitis #Management ... #rheumatology