8 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
to GBM disruption ... hematuria. ... RBC casts in urine ... #Classification ... #Proteinuria #Nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Dyspnea, Fever, Hematuria ... Systemic lupus erythematosus ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... (non-nephrotic proteinuria ... , hematuria) • ... nephrotic-range proteinuria ... and CNS • Headache
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Diagnosis- Compatible syndrome ... PCR 50% sensitive ... granulomatosis: • EBV-associated ... differential #diagnosis #causes ... #radiology #neurology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... hemolytic-uremic syndrome ... Hematuria may be ... #nephrotic #syndrome ... #nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
• Renal: (AKI, proteinuria ... , hematuria) • ... recent DAN) • EMG/NCS ... Goodpasture's cause ... grade proteinuria
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
multiplex • Hematuria ... , proteinuria, rapidly ... tract, and often causes ... systemic lupus erythematosus ... #rheumatology #classification
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Mononeuritis multiplex • Hematuria ... , proteinuria, Rapidly ... ischemia • Skin: Erythematous ... tract, and often causes ... chorioretinitis, CNS