9 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
to GBM disruption ... hematuria. ... RBC casts in urine ... #Classification ... #Proteinuria #Nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Dyspnea, Fever, Hematuria ... ANCA-positive vasculitis ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... syndrome: • ... Diagnostic of GN or vasculitis ... Brown urine - Proteinuria ... #urology #nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... • Renal: (AKI, proteinuria ... , hematuria) • ... Goodpasture's cause ... grade proteinuria
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
multiplex • Hematuria ... , proteinuria, rapidly ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... #rheumatology #classification
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... hemolytic-uremic syndrome ... Hematuria may be ... #nephrotic #syndrome ... #nephrology
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary
CLINICAL
 • Nephritic syndrome (Casts)
 • Marked proteinuria (may be
• Nephritic syndrome ... (Casts) • Marked ... proteinuria (may ... Leukocyturia • Vasculitic ... GlomeruloNephritis #nephrology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Mononeuritis multiplex • Hematuria ... , proteinuria, Rapidly ... tract, and often causes ... pain and GN Anti-GBM ... • Cogan syndrome
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... (non-nephrotic proteinuria ... , hematuria) • ... nephrotic-range proteinuria ... Antiribosomal P, APLA, PAC