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diagnosis differential renal rheumatology classification glomerular management nephrotic pulmonary syndromes algorithm associated blood brain diseases erythematosus glomerulonephritis gn lesions lupus
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
to GBM disruption ... hematuria. ... RBC casts in urine ... Proteinuria often ... #Nephrology #Diagnosis
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... syndrome: • ... Diagnostic of GN or vasculitis ... Brown urine - Proteinuria ... #urology #nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Dyspnea, Fever, Hematuria ... ANCA-positive vasculitis ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Diagnosis- Compatible syndrome ... PCR 50% sensitive ... granulomatosis: • EBV-associated ... differential #diagnosis #causes ... #radiology #neurology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... • Renal: (AKI, proteinuria ... , hematuria) • ... Goodpasture's cause ... grade proteinuria
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... hemolytic-uremic syndrome ... Nephrocalcinosis causes ... Hematuria may be ... #nephrology
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary CLINICAL • Nephritic syndrome (Casts) • Marked proteinuria (may be
• Nephritic syndrome ... (Casts) • Marked ... proteinuria (may ... Leukocyturia • Vasculitic ... GlomeruloNephritis #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
multiplex • Hematuria ... , proteinuria, rapidly ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... • Cogan Syndrome
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Mononeuritis multiplex • Hematuria ... , proteinuria, Rapidly ... tract, and often causes ... pain and GN Anti-GBM ... chorioretinitis, CNS
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
(non-nephrotic proteinuria ... , hematuria) • ... nephrotic-range proteinuria ... and CNS • Headache ... Antiribosomal P, APLA, PAC
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