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Diagnostic Criteria for Systemic Lupus Erythematosus - ACR and SLICC Criteria

#Diagnosis #Rheumatology #SLE #Lupus #Erythematosus #Criteria
Diagnostic Criteria ... ACR and SLICC Criteria ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus ... #Criteria #ACR
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Lupus Erythematosus ... Highly specific antibodies ... #diagnosis #rheumatology
Lupus is diagnosed using clinical and laboratory diagnostic criteria set by the American College of Rheumatology.
Lupus is diagnosed ... A diagnosis of lupus ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus ... #Criteria #ACR
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus ( ... erythematosus ( ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology ... #diagnosis #differential
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Lupus Erythematosus ... hemolytic anemia #Diagnosis ... #Rheumatology # ... SLE #Lupus #Erythematosus
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... - Diagnosis Manifestations ... SLE-Related Auto-Antibodies ... #Erythematosus ... #differential #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ... antibodies) • ... Anti-cardiolipin (aCl ... glycoprotein I (ß2GP), Lupus ... #diagnosis #associations
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ACLE) • Erythematous ... Differential Diagnosis ... Malignancy (e.g. hematologic ... -70, RNP antibodies ... #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... erythematosus ( ... erythematosus ( ... ANA #patterns #rheumatology ... #diagnosis #differential
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... ) • Systemic lupus ... erythematosus ... scleroderma) - Anti-Scl ... #diagnosis #rheumatology