16 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Aldosterone Release: ACE ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Adverse Effects of NSAIDs
Prostaglandins decreased
 - Gastric mucosal damage with ulcer formation, bleeding, and perforation
 -
decreased excretion of NaCl ... blood pressure, impaired ... #SideEffects #Pharmacology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... vs. 1) • Fewer ACS ... Benefits #SickleCell #pathophysiology ... #pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology #
Septic Arthritis: Pathogenesis and clinical findings
Notes:
- Septic Arthritis is typically monoarticular & the knee is involved
decr blood flow, impaired ... pathogen across all ... SepticArthritis #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
chromosome -> Impaired ... downstream of BTK -> Impaired ... precursor cells -> Impaired ... Inability to produce all ... Agammaglobulinemia #XLinked #pathophysiology
Fibrinolysis. 
Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
and urokinase act ... -antiplasmin), act ... Fibrinolysis #Pathway #Pathophysiology ... #Plasminogen #Pharmacology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
hyperammonemia = Impaired ... myeloma, CML, AML ... deficiency #Ammonia #Pathophysiology
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
inflammation of all ... ocular muscles -> Impaired ... Orbital #Cellulitis #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
filtered Na+/K+/Cl ... filtered Na+ and Cl ... Segments #Function #Pathophysiology ... Tubules #Table #Pharmacology