27 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... MIXED) • ANCA associated ... - MPA • CTD Associated ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Fontan-Associated Liver Disease

By Dr. Andrew Yu @michaelandrewyu via @EmoryGastroHep

#FALD #Fontan #Associated #Liver #Disease #gastroenterology #hepatology #pathophysiology
Fontan-Associated ... Liver Disease ... gastroenterology #hepatology ... #pathophysiology ... #diagnosis #management
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
leukemia (CML) - associated ... Colitis and Crohn’s Disease ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Heme associated ... #Summary #causes
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • ... • Autoimmune diseases ... tachycardia or fever, is associated ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... with established disease ... normal in mild cases ... #treatment #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Secondary form associated ... cryoglobulinemia Associated ... cryoglobulins • Negative causes ... CF: Presence of associated ... #rheumatology #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... decrease in most cases ... leukocytosis with a left shift ... hematuria (without casts ... Diagnosis #Workup #Hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung disease ... and M panel Management ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
clinical syndrome associated ... age, however the disease ... febrile illness associated ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology