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Guillain-Barre Syndrome
An acute polyneuropathy (disorder Of the peripheral nervous System).
Symptoms are Often symmetrical and progress Over
Guillain-Barre Syndrome ... GuillainBarre #Syndrome ... #Diagnosis #Neurology ... #Signs
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Barre Syndrome ... Features Required for Guillain-Barré ... sensory symptoms or signs ... nervous system signs ... #Barre #Syndrome
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... than females Guillain-Barre ... bulbar muscles Guillain-Barre ... • Areflexia Guillain-Barre ... #Barre #Syndrome
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Acute spinal cord injury ... Guillain-Barré syndrome ... in spinal cord injury ... Hyperthyroidism, Serotonin syndrome ... diagnosis #table #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Poliomyelitis, Guillain-Barre ... syndrome, Mononeuritis ... Phrenic nerve injury ... Lambert Eaton Syndrome ... differential #diagnosis #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... SinaiBmoreIMRes #GBS #Guillain ... #Barre #Syndrome ... diagnosis #management #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... or acute kidney injury ... renal bruit or signs ... dysautonomia, and Guillain-Barre ... Syndrome - Dr
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... • Mutism Pathophysiology ... : • Severe injury ... Awareness • Injury ... • Examine for signs