13 results
diagnosis hematology vasculitis algorithm classification management product reactions anemia approach arthritis champs complement cryoglobulins dermatologic dermatology extravascular fever glomerulonephritis gpa
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Mnemonic C - Cryoglobulinemia ... S - Systemic Lupus ... Mnemonic #diagnosis #differential ... #hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... - Differential ... Algorithm Red blood ... IgA, post-strep, lupus ... #Hematuria #Differential
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
causing endothelial injury ... • They can cause ... Cryoglobulins Cause ... (e.g. systemic lupus ... classification #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... • Infections: Malaria ... #differential # ... diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... such as systemic lupus ... pulses, bruis, or blood ... Large Vessel: Blood ... #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... reticularis Differential ... purpura • Mixed cryoglobulinemia ... vasculitis (inflamed blood ... rash #diagnosis #rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... Related Acute Lung Injury ... TRALI): Leading cause ... more likely to cause ... tested include: Malaria
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Related Acute Lung Injury ... TRALI): Leading cause ... tested include: Malaria ... diagnosis #management #hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... tumor • Non-bloody ... Like in this case ... Joint #Pain #MSK #rheumatology ... approach #workup #differential
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