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diagnosis hematology blood differential product reactions crisis erythematosus extravascular fever hemolysis infectiousdiseases intravascular nephrology scleroderma sle src systemic transfusion transfusions
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... usually IgG) (e.g. lupus ... • Infections: Malaria ... #anemia
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
microangiopathic hemolytic ... anemia (MAHA) ... endothelial cell activation ... • Refractory cases ... #Crisis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Photosensitivity • Malar ... APLA/LAC: • Renal ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, DIC, hypoTN, renal ... Causes purpura & ... tested include: Malaria ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
, DIC, hypoTN, renal ... Causes purpura & ... tested include: Malaria ... Transfusions #diagnosis #management ... #hematology #reactions
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
thrombocytopenia, and renal ... No hemolytic anemia ... Babesiosis • Plasmodium ... of malaria diagnosed ... tests of liver and renal
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