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diagnosis hematology differential management workup oncology reactions alternaria arthritis classification clinical culture disorders extravascular fever hemolysis hemolytic hodgkins infectiousdiseases intravascular
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... • Infections: Malaria ... Extravascular #Causes ... #anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
plateletcount), peripheral blood ... smear, HIV/HCV testing ... PT, aPTT(liver disease ... changes), high MCV anemia ... #Workup #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Crossmatch - involves testing ... Blood products contain ... false negatives on testing ... tested include: Malaria
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... Blood products contain ... false negatives on testing ... tested include: Malaria
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
No hemolytic anemia ... Babesiosis • Plasmodium ... renal function • Blood ... a chest film; blood-smear ... and possibly PCR testing
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... Fibrin degradation products ... result in severe anemia ... of Peripheral blood ... immune hemolytic anemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Myeloproliferative Disease ... Treatment: Goals: Treating ... Syndromes #diagnosis #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... the presence of anemia ... : • Complete blood ... #Rheumatology
Alternaria on Culture Plate and Microscopy Adult w/ aplastic anemia, getting regular blood product infusions. Had Group
Adult w/ aplastic anemia ... , getting regular ... blood product infusions ... fungi (that can cause ... invasive disease
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... genes and gene products ... Workup: • Full Blood ... number of sites of disease
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