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diagnosis hematology blood differential management comparison cppd extravascular gout hemolysis hemolytic infectiousdiseases intravascular transfusion transfusions travel
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... • Infections: Malaria ... Extravascular #Causes ... #anemia
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... S/sx: Fever, flank ... Causes purpura & ... false negatives on testing ... tested include: Malaria
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... Causes purpura & ... Sx include: fever ... false negatives on testing ... tested include: Malaria
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
No hemolytic anemia ... Babesiosis • Plasmodium ... polymerase-chain-reaction ... (PCR) testing of ... and possibly PCR testing
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
Pyrophosphate produced ... A reaction to phagocytosed ... forefoot, ankles, knees ... 12-24 Hours • Fever ... Synovial Fluid Testing
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