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diagnosis hemophagocytic lymphohistiocytosis treatment blood druginduced product reactions sle summary antinxp2 antinxp2dm comparison dermatology dermatomyositis dil erythematosus hemeonc systemic table
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... Leishmaniosis, malaria ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... Manifestations: Malar ... Positive in 60-80% of cases ... #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
signs and symptoms ... • Infection should ... antibiotic therapy should ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... Discontinuation of causal ... Manifestations: Malar ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome caused ... Presentation • Common Signs ... Approach • Initial management ... #Hematology #HemeOnc
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... donors (due to anti-HLA ... tested include: Malaria ... Transfusion #diagnosis #management ... #hematology #reactions
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... & NPSLE rare, Malar ... Discontinuation of causal ... #DIL #rheumatology ... diagnosis #treatment #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... donors (due to anti-HLA ... tested include: Malaria ... Transfusions #diagnosis #management ... #hematology #reactions
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
, and back and shoulders ... (in a shawl sign ... Muscle atrophy may cause ... Dermatomyositis #diagnosis #management ... #rheumatology #
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